Bone Growth - Chongkione Plus

Chongkione plus

Name of product

Chongkione plus(Foodstuff containing HT042)

Form of product

Pastetype

Application

Stature growth of children

Growth disorder or weakness of children

Physical strength improving like anorexia, immunity

Packing

18 ml * 120 pouch / 120 tablets

Feature

Main constituent : Height growth enhancing natural material

HT042 : Clinically tested Bone growth material (patent no. 0847343, PCT, US)

Growth factor (IGF-1, BMP-2) expression ?

Endochondral proliferation in growth plate

All Natural components.

Traditional Korean medicine based.

No side effect

Research &

development

- Herbal medicine research team in the college of east medicine, Kyung hee university and KISTEM of Neumed Inc.

INGREDIENTS

Deer antler, Rehmannia root, Astragali root, Korean ginseng, Chinese yam, Eleutherococcus root, Hoelen, Phlomidis root, Angelica root, Alpinia fruit,

Honey, Xyritol, Xantan gum, Grapefruit Seed Extract, Water

Developing background

ChongkiOnePLUS in Korea, is based on the multiherbmixture enhancing bone growth.

The product was developed by measuring the length of the growth plate in animal tests.

HT042, significantly enhanced height growth in school-aged children in clinical study.

Children.s numerous personal experiences support the function for many years.

Functions

For growing : Helps advance the growth of kids.

Invigorant medicine : Strengthen physical constitution of kids.

Improving functions of brain and the power of memory.

Improving immunity and anorexia

Efficacy

Helps growth in stature of kids in their growing period.

Invigorant stuffs such as antler, ginseng, eleutheroroot help kidsphysically get strengthened.

Improves cognitive and learning ability for kids.

Intake

Pouch type : 18 ml /day

Tablets type : 4 Tablets/day

Features

Product developed under a support of Plant Diversity Research Center in the Ministry of Science & Technology, Korea.

Made of quality of herb medicinal stuffs strictly selected by specialists.

Verified directly the growth of length of bone.

Verified growing effect in stature of kids, equivalent to growth hormone.

Helps grow in stature of kids, with low cost-high efficiency.

Herb medicinal stuffs have no any side effect to growth hormone.

Containing medicinal stuffs which have passed clinical trials.

Not only help growing in stature but also invigorate energy for supplemental effect.

Patent registered in Korea, w/ number 0847343.

Application for international patent PCT/KR2007/006406, US

1. Know-how for development

INTP (Integrated Natural Products Technology Platform)

Traditional medical library has been built based on the clinical trials accumulated, medical informationsrecorded in oriental medical literatures including 껪ong UiBo Gam. and the private medical informationsworldwide. So it is an unique platform of NeuMedfor further development of good medicines through a systematic searching.

2. Short-term measurement of bone growth by using Tetracycline method3.

This method, developed originally by the research team of KISTEM, is a direct measurement of length of bone actually grown, and being approved by Korea Food & Drug Administration as an evaluation method for its efficacy(recorded in a list of guidelines of KFDA) After fluorescent dyeing the grown part of bone by using Tetracycline method, it is possible that actual Length of its grown part can be measured in unit of µmshortly.

calculating group

Growth Hormone

HT042

Cartilage cell has been numerically expanded by IGF-1 secreted from growth hormone, so its manifestation is being increased than that of calculating group.

3. Long-term measurement of bone growth by using Micro-knemometer

This method is to measure a rate of growing before/after internally administer subject to female rats of 3-week old for 5 weeks, and also measuring length of bone in foot by using Microknemometerin order to evaluate its efficacy for growing. (HermanussenM et al., 1995)