KIDS PLUS SAMPLE SPECIFICATIONS
-. Summary of Products
Invigorant product to advance the growth of kids
- Kids plus
Name of product
Kidsplus (Foodstuff containing HT042)
Form of product
Tablet
Application
Stature growth of children
Growth disorder or weakness of children
Physical strength improving like anorexia, immunity
Packing
180 tablets / 1mo
Features
Healthfood
Main constituent : Height growth enhancing natural material
Bone growth and Immune strength (patent no.0890991)
longitudinal bone growth in Growth plate
(published in Phytother. Res.17, 1113-1116, 2003)
Kor.J.herbology18(1),87-92,2003)
HT042 : Clinically tested Bone growth material (patent no.0847343,PCT,US)
Growth factor (IGF-1,BMP-2) expression?
Endochondral proliferation in growth plate
Ca, Vit. D : build and growth of bone and tooth
Zn : immune improvement
Vit. C, E : cell protection from oxygen free radical
Vit. B1, B2, B6 : essential role of carbohydrate and protein metabolism
All Natural components.
Traditional Korean medicine based.
No side effect
Research &
development
- Herbal medicine research team in the college of east medicine, Kyung hee university and KISTEM of Neumed, Inc.
INGREDIENTS
Astragali root, Red ginseng, Chinese yam, Eleutherococcus root, Phlomidis root, Angelica root, Calcium, Zinc, Vitamin B1, B2, B6, C, D, E
-. About Product / Kids plus
Invigorant product to advance the growth of kids
Developing background
Kids plus in Korea, is based on the multiherbmixture, enhancing bone growth. The product was developed by measuring the length of the growth plate in animal tests.
HT042, significantly enhanced height growth in school-aged children in clinical study. Children’s numerous personal experiences support the function for many years.
New substance HT042,advance the growth of kids
Domestic patent registration no. 0847343
Application for USA,12/518,010
Functions
For growing : Helps advance the growth of kids.build and growth of bone and tooth (Ca, Vit. D)
Invigorant medicine : Strengthen physical constitution of kids.
Improving functions of brain and the power of memory.
Improving immunity and anorexia immune improvement (Zn)
Cell protection from oxygen free radical (Vit.C,E)
Essential role of carbohydrate and protein metabolism (Vit.B1,B2,B6)
Efficacy
Helps growth in stature of kids in their growing period.
Invigorant stuffs such as antler, ginseng, eleutheroroot help kidsphysically get strengthened.
Improves cognitive and learning ability for kids.
Dosage
Tablet type : 6 Tablets/day
Features
Product developed under a support of Plant Diversity Research Center in the Ministry of Science & Technology, Korea.
Made of quality of herb medicinal stuffs strictly selected by specialists.
Verified directly the growth of length of bone.
Verified growing effect in stature of kids, equivalent to growth hormone.
Helps grow in stature of kids, with low cost-high efficiency.
Herb medicinal stuffs have no any side effect to growth hormone.
Containing medicinal stuffs which have passed clinical trials.
Not only help growing in stature but also invigorate energy for supplemental effect.
Patent registered in Korea, w/ number 0847343.
Application for international patent PCT/KR2007/006406, US
-. About Product / Kids plus
Invigorant product to advance the growth of kids
1. Know-how for development
INTP (Integrated Natural Products Technology Platform) Traditional medical library has been built based on the clinical trials accumulated, medical informationsrecorded in oriental medical literatures including ‘Dong UiBo Gam’ and the private medical informationsworldwide. So it is an unique platform of NeuMedfor further development of good medicines through a systematic searching.
2. Short-term measurement of bone growth by using Tetracycline method
This method, developed originally by the research team of KISTEM, is a direct measurement of length of bone actually grown, and being approved by Korea Food & Drug Administration as an evaluation method for its efficacy(recorded in a list of guidelines of KFDA) After fluorescent dyeing the grown part of bone by using Tetracycline method, it is possible that actual Length of its grown part can be measured in unit of µmshortly.
3. Long-term measurement of bone growth by using Micro-knemometer
This method is to measure a rate of growing before/after internally administer subject to female rats of 3-week old for 5 weeks, and also measuring length of bone in foot by using Microknemometerin order to evaluate its efficacy for growing. (HermanussenM et al., 1995)
-. Clinical test on growing in stature of kids
Pediatric department of Kyung heeoriental medical center has conducted human experiment on growing in stature of kids subject to 90-odd male/female kids aged between 8-12 years for 12 weeks, by administering liquid-type of products included patented materials for growing in stature, 2 times daily, and checked out their weights, statures, growth hormones, other related factors before/after internally administeration.
Growing in stature of kids is manifested considerably in the test group.
Constant administering of product will be more helpful in growing
of height for kids. This fact was revealed after 8 weeks of administration
- helps growth in stature, activating to the growth factor.
Analysis on growth hormone and growth related factor in blood before/after administration for 12 weeks
Test group(n=45)
Normal range
0 week
12 week
Growth
hormone
(ng/ml)
3.3 ±0.76
2.1 ±0.66
Male : 0.19-3.1
Female: 0.21-3.74
IGF-1
(ng/ml)
350.1 ±29.1
289.4 ±19.7**
Male : 169-395
Female : 198-754
IGFBP-3
(ng/ml)
3096.1 ±83.1
3386.7 ±109.9**
1200-2560
All values : average value ±standard error IGF-1 : insulin-like growth factor-1,
IGFBP-3 : insuline-like growth factor binding factor-3
.** : proved considerable difference in t-test after 0-12 weeks (p?0.01. *** : p?0.001)
Hot Tip :
After 12 weeks of administering, all values from liver and kidney, such as GOT, GPT, BUN, albumin, creatineare manifested in normal, so it can be recommended to kids.
It is possible for long-term administering.
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